{"id":8445,"date":"2024-02-29T09:12:17","date_gmt":"2024-02-29T08:12:17","guid":{"rendered":"https:\/\/www.phage.help\/unkategorisiert\/reassessment-of-historical-clinical-studies-confirms-the-efficacy-of-phage-therapy\/"},"modified":"2026-05-15T09:34:41","modified_gmt":"2026-05-15T07:34:41","slug":"reassessment-of-historical-clinical-studies-confirms-the-efficacy-of-phage-therapy","status":"publish","type":"post","link":"https:\/\/www.phage.help\/en\/bacteriophages\/reassessment-of-historical-clinical-studies-confirms-the-efficacy-of-phage-therapy\/","title":{"rendered":"Reassessment of historical clinical studies confirms the efficacy of phage therapy"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-32x6tg-e759e29a8e0eb5558b4bf7b3134992b3\">\n.flex_column.av-32x6tg-e759e29a8e0eb5558b4bf7b3134992b3{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-32x6tg-e759e29a8e0eb5558b4bf7b3134992b3 av_one_full  avia-builder-el-0  el_before_av_one_half  avia-builder-el-first  first flex_column_div av-zero-column-padding  '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-lt6y7gdy-066ac7a6c9663cff0e979845c26f2d25\">\n.avia-image-container.av-lt6y7gdy-066ac7a6c9663cff0e979845c26f2d25 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-lt6y7gdy-066ac7a6c9663cff0e979845c26f2d25 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-lt6y7gdy-066ac7a6c9663cff0e979845c26f2d25 av-styling- avia-align-center  avia-builder-el-1  avia-builder-el-no-sibling '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" fetchpriority=\"high\" class='wp-image-8446 avia-img-lazy-loading-not-8446 avia_image ' src=\"https:\/\/i0.wp.com\/www.phage.help\/wp-content\/uploads\/2022\/10\/phagen-1.jpg?fit=966%2C543&ssl=1\" alt='' title='phagen'  height=\"543\" width=\"966\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/i0.wp.com\/www.phage.help\/wp-content\/uploads\/2022\/10\/phagen-1.jpg?w=966&amp;ssl=1 966w, https:\/\/i0.wp.com\/www.phage.help\/wp-content\/uploads\/2022\/10\/phagen-1.jpg?resize=300%2C169&amp;ssl=1 300w, https:\/\/i0.wp.com\/www.phage.help\/wp-content\/uploads\/2022\/10\/phagen-1.jpg?resize=768%2C432&amp;ssl=1 768w, https:\/\/i0.wp.com\/www.phage.help\/wp-content\/uploads\/2022\/10\/phagen-1.jpg?resize=705%2C396&amp;ssl=1 705w, https:\/\/i0.wp.com\/www.phage.help\/wp-content\/uploads\/2022\/10\/phagen-1.jpg?resize=128%2C72&amp;ssl=1 128w\" sizes=\"(max-width: 966px) 100vw, 966px\" \/><\/div><\/div><\/div><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-d13j8-8ec0a7dba69d9a0751db5b3f4751da33\">\n.flex_column.av-d13j8-8ec0a7dba69d9a0751db5b3f4751da33{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-d13j8-8ec0a7dba69d9a0751db5b3f4751da33 av_one_half  avia-builder-el-2  el_after_av_one_full  el_before_av_one_half  first flex_column_div av-zero-column-padding  column-top-margin'     ><section  class='av_textblock_section av-lt6y4iy5-6e1ee09cadb6f67ffed6f1e804f6e702 '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock'  itemprop=\"text\" ><p>Due to the increasing prevalence of antibiotic-resistant bacterial strains, phage therapy has become a hot topic in medical research. In the treatment of bacterial infections, bacteriophages offer several advantages over antibiotics, including strain specificity, the absence of severe side effects, and low development costs.<\/p>\n<\/div><\/section><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-2labvo-f577fc243eb07fb44146a0a9c9926b7a\">\n.flex_column.av-2labvo-f577fc243eb07fb44146a0a9c9926b7a{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-2labvo-f577fc243eb07fb44146a0a9c9926b7a av_one_half  avia-builder-el-4  el_after_av_one_half  avia-builder-el-last  flex_column_div av-zero-column-padding  column-top-margin'     ><p><section  class='av_textblock_section av-lt6y4nga-28559780b616dc30e5e0709ccc1a20ec '   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock'  itemprop=\"text\" ><p>However, scientists dismissed the clinical success of early clinical trials in the 1940s, which slowed the adoption of this promising antibacterial application in Western countries. The current study utilized statistical methods commonly employed in modern meta-analyses to re-evaluate early 20th-century studies and compare them with clinical trials conducted in the last 20 years. <\/p>\n<p dir=\"auto\">Bacteriophages &#8211; Review &#8211; September 7, 2022<\/p>\n<p dir=\"auto\">Authors: Luigi Marongiu<\/p>\n<div class=\"js-react-root\"><span class=\"loader-wrapper\"><span aria-expanded=\"false\" aria-haspopup=\"true\" data-testid=\"hover-card-trigger-wrapper\"><a class=\"css-10vvz0j\" tabindex=\"0\" role=\"button\" href=\"https:\/\/orcid.org\/0000-0003-4720-7087\" data-testid=\"inline-card-resolved-view\"><span class=\"css-14tyax2\" data-testid=\"inline-card-icon-and-title\"><span class=\"css-1yitqmp\"><img decoding=\"async\" class=\"smart-link-icon css-fy7h5c\" src=\"https:\/\/orcid.org\/assets\/icons\/favicon.ico\" data-testid=\"inline-card-icon-and-title-image\"><\/span><span class=\"smart-link-title-wrapper css-0\">ORCID<\/span><\/span><\/a><\/span><\/span><\/div>\n<p dir=\"auto\"> <a href=\"mailto:luigi.marongiu@uni-tuebingen.de\">luigi.marongiu@uni-tuebingen.de<\/a>, Markus Burkard, Ulrich M. Lauer, Ludwig E. Hoelzle, Sascha Venturelli sascha.venturelli@uni-<a href=\"http:\/\/hohenheim.de\/\" target=\"_blank\" rel=\"nofollow noopener noreferrer ugc\">hohenheim.de<\/a> Author Info &amp; Affiliations<\/p>\n<p dir=\"auto\">DOI: <a href=\"https:\/\/doi.org\/10.1128\/cmr.00062-22\" target=\"_blank\" rel=\"nofollow noopener noreferrer ugc\">https:\/\/doi.org\/10.1128\/cmr.00062-22<\/a><\/p>\n<\/div><\/section><br \/>\n<div  class='avia-button-wrap av-lt6y5l18-703cba718ee08925990e539b34e5e2f4-wrap avia-button-center  avia-builder-el-6  el_after_av_textblock  avia-builder-el-last '><a href='https:\/\/journals.asm.org\/doi\/10.1128\/cmr.00062-22'  class='avia-button av-lt6y5l18-703cba718ee08925990e539b34e5e2f4 av-link-btn avia-icon_select-no avia-size-small avia-position-center avia-color-theme-color'   aria-label=\"To the study\"><span class='avia_iconbox_title' >To the study<\/span><\/a><\/div><\/p><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":558,"featured_media":8446,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[253],"tags":[],"class_list":["post-8445","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bacteriophages"],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.phage.help\/wp-content\/uploads\/2022\/10\/phagen-1.jpg?fit=966%2C543&ssl=1","jetpack_shortlink":"https:\/\/wp.me\/pazElU-2cd","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.phage.help\/en\/wp-json\/wp\/v2\/posts\/8445","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.phage.help\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.phage.help\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.phage.help\/en\/wp-json\/wp\/v2\/users\/558"}],"replies":[{"embeddable":true,"href":"https:\/\/www.phage.help\/en\/wp-json\/wp\/v2\/comments?post=8445"}],"version-history":[{"count":3,"href":"https:\/\/www.phage.help\/en\/wp-json\/wp\/v2\/posts\/8445\/revisions"}],"predecessor-version":[{"id":8449,"href":"https:\/\/www.phage.help\/en\/wp-json\/wp\/v2\/posts\/8445\/revisions\/8449"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.phage.help\/en\/wp-json\/wp\/v2\/media\/8446"}],"wp:attachment":[{"href":"https:\/\/www.phage.help\/en\/wp-json\/wp\/v2\/media?parent=8445"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.phage.help\/en\/wp-json\/wp\/v2\/categories?post=8445"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.phage.help\/en\/wp-json\/wp\/v2\/tags?post=8445"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}