
Safety and efficacy of a bacteriophage cocktail in an in vivo sinusitis model
The objectives of this study were to evaluate the safety and efficacy of a Pseudomonas aeruginosa (PA) phage cocktail in a sheep model of rhinosinusitis. The sheep rhinosinusitis model was adapted to simulate a PA infection in the frontal sinuses…

Bacteriophages combat multidrug-resistant bacteria in wastewater
The spread of antibiotic-resistant bacteria is a major threat to public health. These bacteria enter the environment when wastewater leaves the treatment plant. The purification steps currently used in wastewater treatment plants are unable…

Antibiotic resistance to be the leading cause of death by 2050
The report published on Wednesday in Nairobi cited numerous examples: For instance, by 2050, antibiotic-resistant infections are expected to be the leading cause of death worldwide. To prevent this, many more people must gain access to affordable…

Phage studies in the USA in 2019
Two clinical phage trials are being conducted in the USA in 2019.
The first study is a trial investigating the efficacy and safety of orally administered bacteriophages for intestinal adherent-invasive Escherichia coli (AIEC) in patients with…

Antibiotic Resistance in the Arctic
We are now finding the effects of excessive antibiotic use even in the Antarctic. Researchers have detected hundreds of different resistance genes in the soil in Antarctica. This gene confers resistance to antibiotics on bacteria. Even the super-gene…

Bacteriophages as Medicinal Products in the Fight Against Infections
Antibiotic resistance is increasing worldwide. To meet this challenge, the development of alternative therapies is urgently required. Consequently, the Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, the Leibniz Institute…

Medicine from Wastewater: “Phages Are Globetrotters”
Berlin - Bacteriophages are currently receiving increased scientific attention as they are being considered as an alternative to antibiotics. In the age of antibiotic resistance, 33,000 people die annually across Europe as a result of bacterial…

Multidrug-resistant bacteria: Second patient dies in Dresden-Neustadt hospital
Another patient infected with a multidrug-resistant bacterium has died in a Dresden hospital, according to an announcement by the Dresden-Neustadt Municipal Hospital. The patient had previously been treated with so-called reserve antibiotics.…
