Phages saved my daughter’s life – Phage Therapy

A cocktail of phages saved the life of a teenager who had a deadly and seemingly untreatable infection.

Isabelle’s body was attacked by bacteria, and she was given less than a 1% chance of survival.

However, doctors at Great Ormond Street Hospital tried an untested phage therapy, in which viruses are used to infect and kill bacteria.

The phage therapy was a complete success. Isabelle is now learning to drive and studying for her A-levels.

Experts said the case was enormously exciting and demonstrated the potential for treating other dangerous infections with phages.

 

The full story here:
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Bacteriophage

Successful treatment of an antibiotic-resistant bone infection with phages and antibiotics

A patient with an infection of the left tibia with XDR Acinetobacter baumannii and MDR Klebsiella pneumoniae was treated with bacteriophages and antibiotics.

After a short time, an improvement in the tissue was observed. The pathogens could be lysed or killed with phage therapy. This made it possible to save the patient’s leg.

Nir-Paz R, Gelman D, Khouri A et al. Successful treatment of antibiotic resistant poly-microbial bone infection with bacteriophages and antibiotics combination // Clinical Infectious Diseases, Published: 14 March 2019, ciz222. https://doi.org/10.1093/cid/ciz222