Due to the increasing prevalence of antibiotic-resistant bacterial strains, phage therapy has become a hot topic in medical research. In the treatment of bacterial infections, bacteriophages offer several advantages over antibiotics, including strain specificity, the absence of severe side effects, and low development costs.
However, scientists dismissed the clinical success of early clinical trials in the 1940s, which slowed the adoption of this promising antibacterial application in Western countries. The current study utilized statistical methods commonly employed in modern meta-analyses to re-evaluate early 20th-century studies and compare them with clinical trials conducted in the last 20 years.
Bacteriophages – Review – September 7, 2022
Authors: Luigi Marongiu
luigi.marongiu@uni-tuebingen.de, Markus Burkard, Ulrich M. Lauer, Ludwig E. Hoelzle, Sascha Venturelli sascha.venturelli@uni-hohenheim.de Author Info & Affiliations
