Blog – Current Topics on Bacteriophages
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Can bacteriophages help patients with coronavirus infections?

Scientists involved in the study of bacteriophages and their potential for therapeutic applications are considering whether bacterial viruses can somehow help due to the global spread of COVID-19—a disease caused by the novel coronavirus…

Efficacy of phages in an A. baumannii wound infection model in mice

The spread of multidrug antibiotic resistance (MDR) is a widely recognized crisis in the treatment of bacterial infections, including those occurring in military communities. Recently, the World Health Organization published its first list of…

Deadly germs – when antibiotics no longer work

Interesting Arte documentary on deadly germs and phages

Study on the Safety of Bacteriophage Therapy in Severe Staphylococcus aureus Infection

In this non-comparative study, 13 patients in an Australian hospital with severe Staphylococcus aureus infections received intravenous administration of a good manufacturing practice-quality preparation of three Myoviridae bacteriophages (AB-SA01)…

Bacteriophages and Biofilm

Biofilms are an extremely common adaptation that allows bacteria to colonize hostile environments. They present unique challenges for antibiotics and biocides, due both to the nature of the extracellular matrix and the presence of metabolically…

Bacteriophages and Biofilm

Biofilms are an extremely common adaptation that allows bacteria to colonize hostile environments. They present unique challenges for antibiotics and biocides, due both to the nature of the extracellular matrix and the presence of metabolically…

New Insights into the Gut Microbiota

The gut microbiota plays a crucial role in human health. Over the past decade, the viral fraction of the gut microbiota, which essentially consists of phages that infect bacteria, has gained increasing importance. In parallel with the development…

Are lytic bacteriophages the secret weapon for killing Staphylococcus aureus?

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most threatening microorganisms to global human health. Current strategies to reduce the impact of S. aureus include restrictive control of global antibiotic use, prophylactic…

Bacteriophages can fight diseases in aquaculture.

Bacteriophages would be a good tool in aquaculture facilities, say scientists in Finland, after discovering that the viruses survive up to 21 days in recirculating aquaculture systems and could be a long-term solution against bacterial diseases. Theoretically,…

Using phages to combat alcohol-related liver damage?

"Treatment options for alcoholic hepatitis, a liver disease associated with heavy alcohol consumption, are limited. Studies in mice show that the microorganisms responsible for this condition can be targeted with a viral treatment. In 1984,…

Phage-Specific Diverse Effects of Bacterial Viruses on the Immune System

"With the increasing threat of antibiotic resistance, interest in phage therapy (PT) as a potential solution to this crisis has risen rapidly. Recently, several reports have been published describing successful treatment of patients with life-threatening…

Phage-specific diverse effects of bacterial viruses on the immune system

"With the increasing threat of antibiotic resistance, interest in phage therapy (PT) as a potential solution to this crisis has rapidly grown. Recently, several reports have been published describing successful treatment of patients with life-threatening…

A historical overview of phage therapy as an alternative to antibiotics for the treatment of bacterial pathogens

"With the launch of the new Bacteriophage Journal in early 2011, Alexander Sulakvelidze defined bacteriophages as “the most ubiquitous organisms on Earth, playing a vital role in maintaining the microbial balance on this planet. Indeed, bacteriophages,…

A historical overview of phage therapy as an alternative to antibiotics for the treatment of bacterial pathogens

"With the launch of the new Bacteriophage Journal in early 2011, Alexander Sulakvelidze defined bacteriophages as "the most ubiquitous organisms on Earth, playing a vital role in maintaining the microbial balance on this planet. Indeed, bacteriophages,…

Bacteriophages, Superbugs and the U.S. Soldier

Antibiotic resistance is one of the most pressing public health problems worldwide. Army scientists have developed a new weapon to combat superbugs that can protect soldiers and fight resistance. Bacteriophages, a virus that infects and replicates…
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This gene makes Salmonella resistant to all antibiotics

"Antibiotics were undoubtedly one of the most important medical developments of the 20th century. At the same time, however, they are becoming one of the great challenges of the 21st century. Thanks to very loose prescription practices for human…

Phage cocktail reduces Salmonella on a commercial chicken farm

According to the World Health Organization, Salmonella is one of the most important zoonotic pathogens found in food. Poultry products are considered to be the primary source of Salmonella, which means that Salmonella must be controlled before…
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Antibiotics Contaminate Rivers Worldwide

"The research team searched for residues of 14 commonly prescribed antibiotics in rivers from 72 different countries. Antibiotics were found in almost two-thirds of the samples. Dangerous pollution levels were measured particularly frequently…

Bacteriophages reduce the number of pathogenic Escherichia coli in mice without altering the gut flora

"We conducted a study to (i) investigate the efficacy of a bacteriophage cocktail against Escherichia coli/Salmonella spp./Listeria monocytogenes (preliminarily called FOP) to reduce a human pathogenic E. coli strain O157:H7 in experimentally…